Improvements in medical therapy, carotid-artery stenting, and carotid endarterectomy call into question the preferred ...

The management of carotid-artery stenosis that has not caused recent symptoms — asymptomatic carotid stenosis — has been controversial. Clinical trials that began more than 30 years ago showed a small ...

This feature about a man hospitalized for uncomplicated diverticulitis who is found to have high blood pressure offers a case vignette accompanied by two essays, one supporting watchful waiting and ...

To the Editor: The landmark findings of the CheckMate 816 trial, conducted by Forde et al. (Aug. 21/28 issue), 1 showed a significant survival benefit with neoadjuvant nivolumab plus chemotherapy in ...

Sometimes, as patients near the end of life, eliciting and fulfilling a simple wish can lead to acceptance and a peaceful death — a lesson absorbed by a physician during a week of ice cream.

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 19).

When a patient’s family struggles to grasp what enrolling him in hospice will mean, a physician recognizes the limits of the standard script about hospice care.

We conducted an international, open-label, randomized, blinded-outcome-assessment trial involving 1284 patients who had undergone successful catheter ablation for atrial fibrillation at least 1 year ...

Patients with severe hypertriglyceridemia have an increased risk of acute pancreatitis. The efficacy and safety of olezarsen, an antisense oligonucleotide targeting apolipoprotein C-III messenger RNA, ...

A federal appeals court ruling in United States v. Safehouse may open the door to a new legal defense for harm-reduction interventions in a hostile political climate.

In this multicenter, randomized, open-label, noninferiority trial in South Korea, we assigned patients with atrial fibrillation who had undergone the implantation of a drug-eluting stent at least 1 ...