Background Cadherin-11 is expressed on fibroblasts in joints of RA patients and augments local fibroblast–mediated inflammation, pannus formation and tissue invasion (1). RG6125 is a novel humanized ...

1 Clinical Epidemiology Research and Training Unit, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA 2 Data Coordinating Center, Boston University School of ...

Objective To evaluate new classification criteria for peripheral spondyloarthritis (SpA) in patients with SpA with peripheral manifestations only. Methods In this Assessment of SpondyloArthritis ...

2 Rheumatology Department, Leiden University Medical Center, Leiden, The Netherlands 3 Rheumatology Department, Maastricht University Medical Center, Maastricht, The Netherlands Background The ...

OBJECTIVE To determine the efficacy of the individual components of physiotherapy in subjects with anterior knee pain. METHODS An observer blind, prospective, factorial design randomised controlled ...

Objective: Inflammatory back pain (IBP) is an important clinical symptom in patients with axial spondyloarthritis (SpA), and relevant for classification and diagnosis. In the present report, a new ...

1 Division of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands 2 Rheumatology Research Group, MRC Centre for Immune Regulation, ...

Objectives To evaluate the efficacy of rituximab (RTX) in IgG4-related disease (IgG4-RD) in an open-label pilot trial. Methods We treated 30 IgG4-RD patients with two doses of RTX (1000 mg each). The ...

Objectives To provide the level and trends of prevalence, incidence and disability adjusted life years (DALYs) for rheumatoid arthritis (RA) in 195 countries from 1990 to 2017 by age, sex, ...

7 Genetics and Population Health Division, Queensland Institute of Medical Research, Brsibane, Queensland, Australia 8 School of Population Health, University of Queensland, Herston, Queensland, ...

Objective To estimate the global burden of hip and knee osteoarthritis (OA) as part of the Global Burden of Disease 2010 study and to explore how the burden of hip and knee OA compares with other ...

Center for Chronic Disease Outcomes Research at the VA Medical Center, Minneapolis, Minnesota, USA Objective: To better understand the impact of gout on functional status, health-related quality of ...