Yemen’s Houthi rebels are stepping up their missile attacks, keeping up what could be the last major front in the Middle East wars.

Yemen’s Houthi rebels issued a new threat to Israelis saying they won’t cease anti-Israeli operations. A high-ranking Houthi officials threatened Israelis to go back to places from where they came, if they want to sleep peacefully.

Israel said it had repelled an attack, which came hours after Israel’s defense minister vowed to “behead” the Yemeni group’s leadership.

Israel’s military says it intercepted a missile fired toward the country by Yemen’s Houthi rebels. The attack set off sirens late Monday in central areas of Israel, including Tel Aviv.

The US military on Tuesday said it hit targets in Yemen targeting the Houthi militia, hours after the Iran-backed group launched attacks on Israel. The United States Central Command (CENTCOM) said its warships and aircraft attacked a number of Houthi-linked sites,

The military said the missile was intercepted before crossing into Israeli territory, but police reported shrapnel from the interception fell in several towns. There were no reports of injuries.

The assault killed at least four people and injured 21 others, the state news agency in Yemen reported. The strikes came after a week of attacks by the Iran-backed militia.

Approximately 77 people were killed and 145 injured over the past 24 hours in Gaza, the Hamas-run Gaza Ministry of Health said Friday. Israeli air forces struck "approximately 40 Hamas terrorist gathering points" throughout the Gaza Strip over the past day,