Celebrities are increasingly open about using weight-loss drugs like Ozempic and Mounjaro, originally for diabetes, to achieve dramatic transformations. Stars like Lizzo, Amanda Bynes, Meghan Trainor, ...

Oprah Winfrey's decades-long weight loss journey, marked by public scrutiny and personal challenges, took a turn after knee ...

The overarching commonality is that there isn't one: "Not all people experiences the same degree of facial and body changes ...

The study found that GLP-1 medications, in particular, showed significant weight regain after treatment discontinuation.

Watch "An Oprah Special: Shame, Blame and the Weight Loss Revolution" on Monday, March 18 on ABC at 8 p.m. EDT. Disney is the parent company of ABC News and this station.

The explosive popularity of GLP-1 weight-loss medications such as Ozempic®, Wegovy®, and Mounjaro® has transformed obesity care and created an unexpected cosmetic challenge. Rapid fat loss can leave ...

Lizzo admits that she "tried" Ozempic and other GLP-1 medications to help achieve her weight loss goals before deciding they weren't necessary for her to get the results she wanted.

Weight loss drugs like Ozempic and Wegovy are used by over 15 million adults in the U.S., or 4.5% of the population. Despite their effectiveness, they have drawbacks.