cirm.ca.gov

Genetically Modified Hematopoietic Stem Cells for the Treatment of Danon Disease

Research Objective We propose to discover a novel, genetically modified hematopoietic stem cell based treatment for Danon disease, a rare lysosomal storage disease that affects the heart. Impact As ...
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MitoScribe single-cell molecular recorder logs graded signaling dynamics into mitochondrial DNA.

Genetically encoded DNA recorders convert transient biological events into stable genomic mutations, offering a means to reconstruct past cellular states. However, current approaches to log historical ...
cirm.ca.gov

CIRM approves over $160M to support preclinical and clinical research, advances education opportunities and access to clinical trials

South San Francisco, CA, December 11, 2025 – The California Institute for Regenerative Medicine (CIRM) governing board today approved funding of over $160 million for 16 new research awards to develop ...
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CIRM funds clinical research in heart failure and cystic fibrosis, supports 10 new translational projects

South San Francisco, CA, May 30, 2024 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, has awarded $53 million ...
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CIRM Awards Nearly $100 Million to Boost Discovery, Translational, and Clinical Disease Research

South San Francisco, CA, January 30, 2025 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, has awarded nearly ...
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Research Training Grant

The mission of California Institute for Regenerative Medicine (CIRM) is to accelerate stem cell treatments to patients with unmet medical needs. The overall objective of the CIRM Research Training ...
cirm.ca.gov

CIRM approves $8 million award for plasma cell disorder therapy, $27 million to boost collaboration among California researchers

South San Francisco, CA, July 25, 2024 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, awarded nearly $35 ...
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CIRM approves $73 million in awards for discovery research

South San Francisco, CA, September 25, 2025 – The California Institute for Regenerative Medicine (CIRM) has approved awarding more than $73 million across 23 grants to support discovery research ...
cirm.ca.gov

CIRM awards $8 million to advance vision loss gene therapy to clinical trials

South San Francisco, CA, April 24, 2025 — The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, has approved awarding ...
cirm.ca.gov

CIRM awards $4.7 million for vision loss gene therapy

South San Francisco, CA, May 29, 2025 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, awarded $4.7 million to ...
cirm.ca.gov

CIRM awards $27 million to launch novel program designed to bring cell and gene therapies to underserved California communities

South San Francisco, Calif., October 30, 2025 – The California Institute for Regenerative Medicine (CIRM) has approved awarding $27 million through three grants across the state to create a network of ...
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CIRM Announces Recommendations from Strategic Allocation Framework

South San Francisco, CA, September 27, 2024 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutes dedicated to regenerative medicine, announced key ...