cirm.ca.gov

CIRM approves new $100 million plan to accelerate genetic therapies for patients with rare diseases

South San Francisco, Calif., January 30, 2026 – The California Institute for Regenerative Medicine (CIRM) has approved a new funding program to accelerate therapies for rare diseases, which sets aside ...
cirm.ca.gov

Challenges in HIV-1 Latent Reservoir and Target Cell Quantification in CAR-T Cell and Other Lentiviral Gene Modifying HIV Cure Strategies.

Gene-modification therapies are at the forefront of HIV-1 cure strategies. Chimeric antigen receptor (CAR)-T cells pose a potential approach to target infected cells during antiretroviral therapy or ...
cirm.ca.gov

Alexis Carlsson

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Capitol Impact Consulting, LLC

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2026 CIRM SPARK Annual Meeting

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WNT和BMP信号通路在iPSC向iTen细胞逐步分化以进行肌腱修复中的作用

在脊椎动物胚胎发生过程中，轴向肌腱从轴旁中胚层发育而来，并经过特定的发育阶段分化至肌腱节阶段。虽然信号通路在分化早期阶段的主要作用已得到充分证实，但从肌腱节阶段开始，肌腱 ...
cirm.ca.gov

鸟类内耳感觉毛细胞再生的解剖学和分子生物学见解。

与哺乳动物不同，鸟类能够再生内耳毛细胞，修复听力损伤。为了将鸟类修复听力的机制应用于人类，比较鸟类和哺乳动物内耳毛细胞的叫声将有助于我们找到修复人类听力损伤的方法。
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唐氏综合征患者皮质神经发生速度加快。

唐氏综合征（DS）由21三体综合征（TS21）引起，是导致智力障碍的最常见遗传病因(1,2)。DS的神经系统影响首先在产前发育阶段显现，表现为放射状胶质细胞（RG）神经干细胞增殖减少、皮质体积 ...