As a No. 12 seed, they find themselves in one of the most common upset spots, as 12-seeds have a long history of knocking off No. 5 seeds in the first round. Led by star guard Nique Clifford, who is averaging a career-high 19.0 points per game, Colorado State has the firepower to make a run.

Their proven projection model has simulated every game in the tournament 10,000 times. It has absolutely crushed its March Madness picks recently, beating over 91 percent of all CBS Sports brackets in four of the past six tournaments.