Aerobic glycolysis dominates lesion bioenergetics, with lactate promoting histone lactylation, M2 macrophage polarization, CD8⁺ T-cell exhaustion, EMT, and fibrosis that reinforce immune-protected ...

Sepsis, a life-threatening condition caused by dysregulated host response to infection, remains a major cause of global ...

Phosphatidate phosphatase (PAP) enzymes play a pivotal role in lipid metabolism, acting as a control point that directs metabolic flux between membrane phospholipid synthesis and the production of ...

Could a Mediterranean diet reduce Alzheimer’s risk for some people more than others? I unpack a new study that shows why ...

Neurons carry vital signals all over our body, and the nervous system controls many crucial functions, from breathing to ...

1. What's so special about plant lipids? / J.L. Harwood -- part I. De novo fatty acid biosynthesis. 2. Biotin-dependent carboxylases and their biotinylation in higher plants / C. Alban and R. Douce. 3 ...

Sepsis, a life-threatening condition caused by dysregulated host response to infection, remains a major cause of global ...

Hypertensive disorders of pregnancy are the leading cause of maternal mortality worldwide, yet they are typically only ...

This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells ...

Obesity is characterized by excessive energy storage in white adipose tissue, whereas increasing energy expenditure through ...