Centrioles and basal bodies (hereafter referred to as 'centrioles' for simplicity) are essential for the formation of cilia, flagella and centrosomes. Therefore, understanding the mechanisms governing ...

Centrioles are cylindrical structures involved in the generation of microtubules - fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes ...

Tubulin superfamily members are essential for maintaining the microtubule cytoskeleton. α- and β-tubulin form the basic subunit of the microtubule polymer and assembly of microtubules is nucleated at ...

Biologists at the National University of Singapore (NUS) have uncovered how the protein NuSAP safeguards tiny structures inside cells called centrioles, revealing a mechanism linked to developmental ...

A two-step recruitment model based on the findings for the CEP57-CEP63-CEP152 complex during a single cell cycle. (A) During S to G2 phase, CEP57 is gradually recruited to the procentriole, crucial ...

Mitosis is the process by which the genetic information encoded on chromosomes is equally distributed to two daughter cells, a fundamental feature of all life on earth. Scientists now examine how ...

EPFL scientists discover that certain cell structures, the centrioles, could act as information carriers throughout cell generations. The discovery raises the possibility that transmission of ...

Centrioles, the barrel-shaped organelles best known for their role in cell division, may also put their stamp on early embryos. In a newly fertilized embryo, the centrioles that are present come ...

Human sperm cells are well-studied, so scientists were completely surprised to find a previously unknown structure in the little swimmers. And perhaps more surprising, this newfound structure may ...

Researchers have captured the assembly of the NLRP3 inflammasome inside intact human cells for the first time. These ...

Scientists say they have discovered critical features of cancer cells that may help clinicians better fight the disease. The researchers found that the number and size of centrioles are increased in ...