Figure 1: Inherited duplications and triplications of the α-tryptase–encoding sequence in the TPSAB1 gene are associated with elevated basal serum tryptase levels and enhanced mast cell secretion of ...

Please provide your email address to receive an email when new articles are posted on . Patients with alpha tryptase had more anaphylaxis than patients who only had B-tryptase. 65% of patients with ...

In a decade-long study, a ratio of serum acute tryptase to serum baseline tryptase above 1.74 showed superior diagnostic performance compared with the current consensus formula, which requires serum ...

Among adults with evidence of systemic mast cell activation, bone marrow samples allowed for detection of 13 additional ...

Reference ranges for basal serum tryptase (BST) are an excellent guide to determining whether a patient’s BST value is normal, per their specific tryptase genotype. If the BST is elevated based on the ...

Researchers reported for the first time that a genetic biomarker may be able to help predict the severity of food allergy reactions. Currently there is no reliable or readily available clinical ...

Adequacy of biopsy samples for molecular testing in patients with non-small cell lung cancer. Analyses of the immunologically relevant gene transcript by qRT-PCR in primary cutaneous melanoma by the ...

--Data strongly support expanding development into mast cell driven diseases----Data presented in a late-breaking session at EAACI Annual Congress 2020-- CDX-0159 demonstrated a favorable safety ...

The use of PARP inhibitors as single agents and as chemosensitizers in sporadic pancreatic cancer. Farletuzumab, a monoclonal antibody against folate receptor alpha (FRα), does not block folate or ...

The diagnosis of anaphylaxis can be tricky, especially in the absence of known triggers and when other conditions, such as urticaria and asthma, mimic aspects of the reaction. Biomarkers can help to ...