Once in every cell cycle microtubules become organized into a bipolar spindle that segregates the replicated chromosomes to the two daughter cells 1,2. Two models, which are not mutually exclusive, ...

The orientation of cell division is tightly regulated to ensure proper tissue morphogenesis and to prevent cancerous growth. Cell division can be symmetric resulting in two equal daughter cells and ...

Scientists have gained new insight into the formation of the spindle, which is the molecular machine that divides up genetic material prior to cell division. Their work focuses on the motor protein, ...

The findings shed light on the mechanisms behind "self-organization" - an essential characteristic of biological structures. Organisms are composed of a variety of structures including muscles, ...

Cambridge, Mass. - April 26, 2012 - The mitotic spindle, an apparatus that segregates chromosomes during cell division, may be more complex than the standard textbook picture suggests, according to ...

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have identified a signaling pathway that restricts cleavage furrow formation to the mid-plane of the cell. Cell division is a ...

Accurate mitotic chromosome segregation depends on the formation of a microtubule-based bipolar spindle apparatus. We report that the cohesin subunit structural maintenance of chromosomes subunit 1 ...

The molecular machinery that propels cell division consists of parts that are, by now, fairly familiar. How the parts work together, generating and transmitting power as needed, is less clear. To see ...

Heart development: Researchers at the Max Planck Institute for Heart and Lung Research have discovered important mechanisms for regulating embryonic heart development. The proteins RBPMS and RBPMS2 ...

The mitotic spindle, an apparatus that segregates chromosomes during cell division, may be more complex than the standard textbook picture suggests. The mitotic spindle, an apparatus that segregates ...