Elevated NfL levels tracked with poorer cognitive scores and higher death risk in centenar ...

A team at Kindai University in Osaka, Japan, fed ordinary L-arginine to fruit flies and mice engineered to develop ...

Beta-amyloid plaques are considered a hallmark of Alzheimer’s disease, but they’re not the sole cause of the disease and its symptoms. Alzheimer’s is a complicated disease that experts are still ...

A longitudinal cohort study showed that a higher amyloid-beta (Aβ) load in centenarians was associated with poorer cognitive performance, particularly executive functioning. Two thirds of centenarians ...

Piller is an investigative journalist for Science. In November 2022, Dennis Selkoe, a Harvard professor of neurologic diseases and among the most celebrated and prolific Alzheimer’s researchers, ...

A major review challenges a long-standing strategy in Alzheimer’s research, suggesting that removing a hallmark brain protein ...

Endogenous lithium may have a physiological role that affects brain aging and vulnerability to Alzheimer's disease, postmortem human samples and mouse experiments suggested. Of 27 abundant and trace ...

Amyloid β is the cleavage product of Amyloid Precursor Protein (APP). Long suspected a culpable player in Alzheimer disease progression due to the plaques it forms, Aβ may have a physiological role ...

While amyloid β plaques are hallmarks of Alzheimer’s disease (AD), recent research suggests that they aren’t the only players in the neurodegenerative disorder. Genome-wide association studies and RNA ...

Medications like lecanemab (Leqembi) and donanemab (Kisunla) target amyloid plaques in the brain that build up due to Alzheimer’s disease. They may help slow disease progression for people in the ...

But “deep sleep keeps Alzheimer’s symptoms at bay” is not what this evidence proves. A more honest headline would be: “Deep ...