At 6-5 with a playoff berth within reach, the Carolina Panthers roll into primetime carrying equal parts urgency and belief. Across the field, the 7-4 San Francisco 49ers enter Monday night trying to steady themselves after an uneven stretch,

Week 12 of the 2025 NFL season concluded with a matchup that carried playoff implications for both teams as the San Francisco 49ers (8-4) defeated the Carolina Panthers (6-6) on Monday Night Football.