W hen the 2025 NFL schedule came out in May, the Cleveland Browns should have filed a protest and asked the league to redo Week 6, because the Browns have been hit with a brutal scheduling quirk that only one other team in NFL history has ever had to face.

This weekend, teams favored by a touchdown or more include the Broncos (-7.5) over the Jets in London, the Colts (-7) over the Cardinals, the Rams (-7.5) over the Ravens and the Packers (-14) over the Bengals.

Should I start Chase Brown, Quinshon Judkins, J.K. Dobbins for Week 6? Fantasy football start 'em, sit 'em picks and recommendations for the 2025 NFL season.

USA Today's NFL experts make their picks for a Week 6 showdown between the Green Bay Packers and Cincinnati Bengals

The Cleveland Browns continue to find ways to lose in heart-breaking fashion, spoiling Dillon Gabriel's NFL debut vs. the Minnesota Vikings

Week 6 kicks off at MetLife Stadium on Thursday Night Football when the Eagles travel to the Giants in what should be a fun NFC East divisional matchup. While the weather can often get tricky at MetLife Stadium later in the season, the weather should be pretty solid for this tilt.

For one, the Browns have one of the best defenses in football, allowing a league-low 57.3 rushing yards per game through their first three games. For another, Cleveland is coming off a surprising 13-10 win over the Green Bay Packers in Week 3, beating the only team that has beaten the Lions so far this season.

The New York Giants and Philadelphia Eagles face off in Week 6 of the NFL regular season today. Here's where to watch and start time.