Also, let's not ignore the tremendous season that Sam Darnold is putting together for the Seahawks. Remarkably, his completion percentage and passer rating are even better than what he produced last season with the Vikings. I think he leads Seattle into Duval County and leaves with an outright win.

The Bengals and Ravens are both missing their quarterbacks, but so are the 49ers. It could get worse for Cincy and Baltimore this week.

Here are score predictions for Detroit’s road matchup with the Chiefs from MLive’s beat writers: These Lions and Dan Campbell are built for games like this -- primetime, football world watching against a perennial contender.

Week 6 has plenty of intriguing matchups on deck, and already is off the heels of the New York Giants upsetting the Philadelphia Eagles on Thursday night. That just goes to show you that anything can unfold after kickoff,