SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each player prop for NFL Week 6

Get the full Week 6 NFL injury report featuring key updates on Lamar Jackson, Ja’Marr Chase, Alvin Kamara, and other fantasy football stars you need to monitor.

ABC News’ Lara Spencer has all highlights from Sunday’s games, including the matchup between the Philadelphia Eagles and the Buffalo Bills.

A week after seizing control of the AFC South with a shootout victory over the Seattle Seahawks 38-35, the Tampa Bay Buccaneers will face another stiff test when they battle the NFC West-leading San Francisco 49ers (+3).

As good as Darnold was, Tampa Bay quarterback Baker Mayfield was even better, going 29-for-33 for 379 yards and two touchdowns. His 11-yard touchdown pass to Sterling Shephard with 1:08 to play tied the score at 35 and set the stage for the win.

An eventful Sunday in the NFL was headlined by the second highest-scoring tied game in league history and a big win for the Kansas City Chiefs over the Baltimore Ravens.

Content on this page may include affiliate links. If you click and sign up/place a wager, we may receive compensation at no cost to you. The Week 5 NFL schedule includes 12 games on Sunday, including a rapid-fire six-game window at 1 p.

How teams are trending after Sunday of Week 5 resulted in stunning upsets and improbable comebacks — often in the same game.