The Chiefs have already lost to the Chargers, Eagles and Jaguars, and now, they get their toughest test of the season in the Detroit Lions. The Lions will be rolling into Kansas City on a four-game winning streak, which is currently the longest in the NFL.

Frank Ammirante's five fantasy football bold predictions for Week 6 of the 2025 NFL season. Expert predictions for Bryce Young, Jacory Croskey-Merritt, Tucker Kraft, and more.

The Bengals and Ravens are both missing their quarterbacks, but so are the 49ers. It could get worse for Cincy and Baltimore this week.