Sarcomas, a diverse group of malignancies, exhibit substantial heterogeneity in both biological behavior and microenvironment, influencing their response to immunotherapy. Although pembrolizumab is ...

Please provide your email address to receive an email when new articles are posted on . First-line immunotherapy of microsatellite instability-high metastatic colorectal cancer improved survival ...

CHICAGO--(BUSINESS WIRE)--Cellworks Group Inc., a leader in Personalized Therapy Decision Support and Best-in-Class PTRS, today announced compelling results from a new study demonstrating the ability ...

Compared with chemotherapy, immune checkpoint inhibitors (ICIs) were associated with improved overall survival in patients with microsatellite instable metastatic colorectal cancer (CRC), particularly ...

A new microsatellite instability (MSI) system by Promega, the LMR MSI Analysis System, enables cancer researchers a broader view of mismatch repair deficiency (dMMR). An expanded set of MSI markers ...

Opdivo® (nivolumab) in combination with Yervoy® (ipilimumab) has been made available within NHS Scotland for the first line treatment of adult patients with mismatch repair deficient (dMMR) or ...

To assess implementation of a next-generation sequencing (NGS) assay to detect microsatellite instability (MSI) as a screen for Lynch syndrome (LS) in endometrial cancer (EC), while determining and ...