New research has uncovered immune changes in cancer patients that could help identify which patients are most at risk of dangerous heart complications from cancer drugs, known as immune checkpoint ...

Immune checkpoint inhibitors are among the most successful treatments developed for advanced cases. These drugs work by removing the brakes on immune cells, allowing them to attack cancer. The most ...

BOSTON, June 13, 2025 — Pembrolizumab, an immune checkpoint inhibitor, has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of patients with resectable locally advanced ...

For many people diagnosed with cancer, treatment with immune checkpoint inhibitors (ICIs) has dramatically extended lives. Some of these treatments, such as Keytruda and Opdivo, have become familiar ...

Immune checkpoint inhibitors have reshaped cancer treatment over the past decade, but the same immune activation that shrinks tumors can also turn against healthy tissue, including the brain. A ...

Bi/multispecific drugs in oncology present key opportunities: precision targeting, innovative immune modulation, and personalized therapies. With rapid pipeline growth, breakthrough approvals, and ...

How reorganizing existing drugs and vaccine components can dramatically alter their potency, selectivity, and even their ...

A new study from Moffitt Cancer Center brings fresh hope to patients battling advanced melanoma who aren’t helped by today’s best treatments. Researchers have found a powerful combination of three ...