The prevalence of obesity is steadily rising and has huge health and financial implications for society. Weight gain is due to an imbalance between dietary intake and energy expenditure and research ...

In a mouse model, progestin-primed ovarian stimulation suppressed the preovulatory luteinizing hormone surge by remodeling ...

Hypothalamic obesity (HyOb) develops when damage to the hypothalamus — from brain tumors, traumatic brain injury, radiation therapy, or stroke — disrupts how your body regulates appetite and ...

We investigated the role of hypothalamic insulin signaling in the regulation of energy balance and insulin action in rats through selective decreases in insulin receptor expression in discrete ...

Obesity associated with hypothalamic dysfunction was initially described in patients with craniopharyngioma. Hypothalamic obesity may also result from brain radiation, infection (eg, tuberculosis), ...

Please provide your email address to receive an email when new articles are posted on . The FDA approved an expanded indication for setmelanotide for acquired hypothalamic obesity. The drug conferred ...

Please provide your email address to receive an email when new articles are posted on . Setmelanotide was linked to reduction in BMI at 52 weeks compared with placebo for patients with acquired ...

Adults with narcolepsy type 1 had smaller hypothalamic volumes than matched controls, 807.1 vs 847.6 mm3, in the largest MRI study of its kind. The anterior subregions shrank most, but the ...

The brain controls the release of glucose in a wide range of stressful circumstances, including fasting and low blood sugar levels. However, less attention has been paid to its role in day-to-day ...

Missed periods for months, but scans and tests come back normal? Hypothalamic amenorrhoea, a hormonal condition often triggered by stress, inadequate nutrition, weight loss, or excessive exercise, may ...

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