Defects in the protein Sox10, a transcription factor that regulates gene expression, may play a role in the development of post-operative GI dysfunction in Hirschsprung's disease patients, according ...

A manometric technic is described for the diagnosis of Hirschsprung's disease without the necessity of deep-muscle rectal biopsy. Separate pressure recordings were obtained from the internal and ...

It’s not uncommon for children to experience occasional tummy troubles. Sometimes it’s something they ate, and other times they may simply not be feeling well. And from time to time, everything from ...

Hirschsprung's disease is a rare congenital condition that affects bowel movements due to missing nerve cells in parts of the intestine. Here's a comprehensive breakdown of its types, causes, and ...

Researchers at the University of Helsinki have developed a new mouse model of Hirschsprung’s disease and associated enterocolitis and shed light on the disease progression. About one in every 5,000 ...

When doctors in China removed 30 inches of a young man's colon, they also removed nearly 29 lbs. (13 kilograms) of his feces. The 22-year-old's belly had swelled past the size that would be seen in a ...

Hirschsprung's disease is a rare condition that prevents a person from pooping normally. Babies with Hirschsprung's are missing the nerve cells needed to push digested food out of their colon (the ...

Researchers have developed a new mouse model of Hirschsprung's disease and associated enterocolitis and shed light on the disease progression. About one in every 5,000 babies is born without enteric ...

Treatment for Hirschsprung disease typically involves a surgical procedure known as a pull-through procedure to remove a section of the colon. Some people may also need ostomy surgery. Hirschsprung ...