PURPOSE: Time to progression (TTP), overall survival, and quality of life (QL) were compared in patients with hormone-resistant prostate cancer (HRPC) treated with prednisone (5 mg orally, four times ...

Efficacy of triptorelin in lowering serum testosterone (sT) in patients with advanced prostate cancer. Background: PSA-TRICOM is a vector-based, therapeutic cancer vaccine regimen consisting of ...

Learn everything you need to know about Flutamide-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it. Get up-to-date information on side effects, precautions, warnings, ...

Review the side-effects of Flutamide as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the ...

Background: Flutamide has been rarely used for the treatment of female pattern hair loss (FPHL). Flutamide treatment for FPHL has not been evaluated in long-term studies with sufficiently large ...

Evidence indicates that flutamide, a specific and potent androgen-receptor blocker, when given in low dose (∼1 mg/kg daily), confers a first-choice balance between antiandrogenic efficacy and hepatic ...

Antiandrogens are a group of medications which bind to intracellular androgen receptors (AR) to prevent androgen effects on organs such as the testes, the hair follicles, the hypothalamus, pituitary, ...

Flutamide (FLT) is an antiandrogen drug for the treatment of prostate cancer. It has the drawback of poor water solubility and needs enhancement of its dissolution rate in simulated gastric fluids.

It is peculiar that the employment of a potent antiandrogen, such as flutamide, in FPHL has been so underutilized. Recently, Scheinfeld [28] observed that flutamide is not in common use by ...