Fibrin formed as a result of fibrinogen polymerization is the main protein component of a clot in a test tube and intravascular thrombi in vivo. Fibrin clot structure characterized by fiber diameter ...

Despite improved diagnosis and treatment options, coronary artery disease (CAD) is still the leading cause of mortality and morbidity worldwide. Established risk factors such as smoking, ...

Blood clotting is the “Jekyll and Hyde” of biological processes. It’s a lifesaver when you’re bleeding, but gone awry, it causes heart attacks, strokes and other serious medical problems. If a clot ...

Fibrin plays a major role in stopping bleeding and healing wounds. However, if fibrin is formed in excess, e.g., in chronic wounds, thrombosis and subsequent vascular occlusions can occur. Therefore, ...

This scanning electron micrograph of a blood clot -- taken from the coronary artery of somebody who had a heart attack -- might be scary if it weren't so cool. Look closely: The brown mesh is a wiry ...

“Clot-busting” fibrinolytic drugs are administered to patients who have had a heart attack or ischemic stroke. These drugs are delivered systemically or, when possible, locally through a catheter ...

An antibody to the blood-clotting protein fibrin leaves coagulation alone but blocks the ensuing inflammatory cascade. Scientists led by Katerina Akassoglou, Gladstone Institutes, San Francisco, ...