During development, cells become progressively restricted in their lineage choices. The allocation of cells to a specific lineage is regulated by the activities of key signalling pathways and ...

Neural crest cells have been thought to originate in the ectoderm, the outermost of the three germ layers formed in the earliest stages of embryonic development. But their capacity to form derivatives ...

In the upper of the picture, the normal embryo goes through a key morphogenetic step during the transition from blastocyst to egg cylinder that epiblast cells marked by red are transformed into a ...

For several years, researchers studied human embryonic stem cells (ESCs) to understand the unique features of these pluripotent cells, but on their own, they poorly resembled the complex structures ...