Imagine watching your dog waddle into the room and noticing that he is walking on the top of his back paw. While you may classify it as a harmless quirk, in reality, that "knuckling" action can ...

Degenerative myelopathy is a degenerative disease of the spinal cord that begins in older adulthood and progresses slowly until dogs are no longer able to walk unassisted. The cause of the disease is ...

A gene-silencing therapy under development for people with amyotrophic lateral sclerosis (ALS) is being tested at Tufts in dogs with degenerative myelopathy, a fatal paralytic disease that is similar ...

Canine Degenerative Myelopathy (DM) is a neurodegenerative disease in dogs with similarities to ALS in humans. Scientists have discovered a modifier gene that affects the risk of developing DM in ...

In 2009, Joan Coates, a veterinary neurologist, along with other researchers at the University of Missouri and the Broad Institute at MIT/Harvard, found a genetic link between degenerative myelopathy ...

Q: Gretchen, our 9-year-old German shepherd, recently developed hind leg weakness. Her veterinarian recommends testing for degenerative myelopathy. Many years ago, another of our shepherds had ...

Researchers have found that the genetic mutation responsible for degenerative myelopathy (DM) in dogs is the same mutation that causes amyotrophic lateral sclerosis (ALS), the human disease also known ...

The mSOD1 mouse, harboring a mutated human superoxide dismutase (SOD1) gene, has long held the spotlight as the model of choice for amyotrophic lateral sclerosis (ALS). It has yielded scores of papers ...

Canine Degenerative Myelopathy (DM) is a neurodegenerative disease in dogs with similarities to ALS in humans. Scientists at Uppsala University, SciLifeLab and the Broad Institute of MIT and Harvard, ...

COLUMBIA, Mo. –An incurable, paralyzing disease in humans is now genetically linked to a similar disease in dogs. Researchers from the University of Missouri and the Broad Institute have found that ...