- Research published in Molecular Cell used INDUCE-seq to identify DNA topology as an important regulator of CRISPR targeting specificity - Peer-reviewed data demonstrates the sensitivity of ...

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own ...

Inside cells, DNA twists and coils itself into a variety of different secondary structures—including i-motifs (iMs) and ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among ...

Broken String Biosciences (“Broken String”), a genomics company building a technology platform to drive the development of cell and gene therapies that are safer by design, today announced that its ...