Bilirubin, a by-product of haem metabolism, plays a crucial role in human physiology beyond its well-known association with jaundice. Emerging evidence underscores its antioxidant and cell signalling ...

Phenobarbital causes a marked proliferation of the smooth-surfaced membranes of the endoplasmic reticulum in the liver cells. And, like many other compounds, it is an inducer of drug-metabolizing ...

Conjugation of bilirubin and delivery to the intestine doesn't necessarily lead to excretion of the substance. Neonatal intestines contain beta-glucuronidase, an enzyme capable of reducing bilirubin ...

THE formation of bilirubin and its elimination from the body as a waste product of heme catabolism require a series of metabolic alterations and transport processes. Partial or complete failure at any ...